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What is a Lung Transplant and when do you need one?

A lung transplant procedure is undertaken to provide a patient with an end-stage lung failure with a viable & long-term solution alongside a good quality of life. The procedure is carried out when an individual can no longer remain healthy with the diseased lung. In most end-stage diseases, a pulmonary or lung failure is both evidenced and therefore a dual organ replacement becomes a necessity. The common causes of end-stage lung failure include:

  • 1. Pulmonary hypertension (elevated blood pressure within the lungs' blood vessels)
  • 2. Chronic pulmonary obstructive disease
  • 3. Pulmonary fibrosis
  • 4. Cystic fibrosis
  • 5. Severe bronchiectasis

A lung failure results in - shortness of breath, excessive fatigue, inability to carry out everyday tasks, swelling of the limbs and dizziness - amongst other factors. All of this result in an extremely poor quality of life for the patient, in additional to possible fatality if suitable treatment options are not found. A transplant surgery is the most viable and long-term treatment solution for a lung failure. It can either be a single lung transplant or a dual lung transplant. In some cases, doctors suggest a combined heart-lung transplant for improved results.

Why Would you Need a Transplant?

You are being referred for a transplant surgery because you quality of life has been severely affected by a disease. Many types of lung disease may lead to end-stage lung failure. You have developed lung disease that neither medicine nor surgery are able to help. Patients are considered for lung transplantation when their lung disease cannot be significantly improved by either medical or surgical therapy. For some patients, the lung disease may also severely affect the function of the heart. This may mean that a heart-lung transplantation is necessary. Transplant is considered a treatment option when failure of the lungs and heart results in a poor quality of life and life expectancy is severely limited. Lung and heart-lung transplantation is a surgical and medical therapy .that can lead to a better quality of life, improved lung function, and a chance for you to experience a normal lifestyle.

Why Would you Need a Transplant?

You are being referred for a transplant surgery because you quality of life has been severely affected by a disease. Many types of lung disease may lead to end-stage lung failure. You have developed lung disease that neither medicine nor surgery are able to help. Patients are considered for lung transplantation when their lung disease cannot be significantly improved by either medical or surgical therapy. For some patients, the lung disease may also severely affect the function of the heart. This may mean that a heart-lung transplantation is necessary. Transplant is considered a treatment option when failure of the lungs and heart results in a poor quality of life and life expectancy is severely limited. Lung and heart-lung transplantation is a surgical and medical therapy that can lead to a better quality of life, improved lung function, and a chance for you to experience a normal lifestyle.

What are the Diseases That May Be Treated with Lung or Heart-Lung Transplant?

Many different types of disease can lead to end-stage function of the lungs and the heart. In our center at Parkway Global hospitals and across the World, the most commonly treated diseases include: Cystic Fibrosis, Primary Pulmonary Hypertension, COPD, Secondary Pulmonary Hypertension due to heart defects, Bronchiolitis Obliterans, and Interstitial Lung Disease. There are three types of Lung Transplant: Heart-Lung, Double Lung, and Single Lung depending upon the disease progress.

What are the Indications for Single-Lung Transplantation:

  • Pulmonary Fibrosis
  • Pulmonary Hypertension

What are the Indications for Double-Lung Transplantation

  • Pulmonary Fibrosis
  • Primary Pulmonary Hypertension and other types of pulmonary vascular disease
  • Interstitial Lung Disease
  • Cystic Fibrosis
  • Pulmonary hypertension with heart defects that can be surgically repaired
  • Surfactant Deficiency (due to ABCA3 mutations)
  • Surfactant Protein B and Surfactant Protein C Deficiency
  • Bronchiolitis Obliterans

What are the Indications for a combined Heart-Lung Transplantation?

  • Pulmonary hypertension with structural heart defects that cannot be surgically repaired.
  • Patients with severe heart failure who also have one of the conditions listed above.

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